Fast-acting results, proven longevity, and an extensive international track record—what you need to know about this neuromodulator.
Letybo (letibotulinumtoxinA-wlbg) represents a significant advancement in botulinum toxin technology, offering patients a scientifically validated alternative for wrinkle reduction and facial rejuvenation. Health Canada-approved on June 14, 2022, for the treatment of moderate to severe glabellar lines, this South Korean-developed neuromodulator brings over a decade of international clinical experience to Canadian aesthetic practices.
With over 31 million treatments performed worldwide and ranking as the #1 neurotoxin in South Korea, Letybo has established itself as a globally trusted solution backed by robust clinical evidence.
Letybo is manufactured by Hugel, Inc., a biopharmaceutical company recognized as a leader in aesthetic innovation, and is available in Canada through Hugel Canada Inc. The product contains a highly purified botulinum toxin type A with a 900 kDa molecular complex, produced through an enzyme-free purification process. This advanced method removes nucleic acids and enzymes of animal origin, resulting in exceptional purity.
The mechanism of action mirrors other type A botulinum toxins: Letybo temporarily inhibits acetylcholine release at the neuromuscular junction, reducing muscle activity and smoothing dynamic wrinkles.
What distinguishes Letybo is its focused diffusion pattern, offering practitioners enhanced precision when targeting specific muscle groups. This reduced protein load may offer particular advantages for patients requiring long-term treatment.
The safety profile of Letybo aligns closely with the established safety characteristics of botulinum toxin type A products. Local injection site reactions such as mild redness, swelling, and bruising typically resolve within a few days. The treatment process itself is quick and relatively comfortable, with most sessions lasting 10 to 15 minutes. Patients can generally return to normal activities immediately following treatment.
At Sharief Aesthetics, the decision to offer Letybo as a preferred neuromodulator reflects a commitment to providing patients with access to cutting-edge aesthetic technologies backed by robust clinical evidence. As a Health Canada-approved neuromodulator, Letybo represents a significant milestone in aesthetic medicine. Its focused area of activity allows for controlled, predictable results that maintain natural facial expression while effectively addressing dynamic wrinkles.
While Health Canada-approved specifically for glabellar lines, experienced practitioners utilize Letybo for various aesthetic applications, including forehead lines, crow's feet around the eyes, and other dynamic facial wrinkles. The precision formulation of Letybo makes it particularly well-suited for delicate work requiring controlled diffusion.
A comprehensive consultation precedes every Letybo treatment at Sharief Aesthetics, ensuring that treatment plans are tailored to individual needs and desired outcomes. During the procedure, small amounts of Letybo are injected using ultra-fine needles into targeted muscles. Most patients report minimal discomfort.
Letybo offers a compelling combination of clinical evidence, a strong safety profile, fast onset of action, and high-purity. For patients seeking a neurotoxin with a rapid onset, a proven global safety record, and precise diffusion, Letybo's scientific profile and extensive international experience make it a compelling choice.